Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2- hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells

Zoltán Hujber, Gábor Petővári, Norbert Szoboszlai, Titanilla Dankó, Noémi Nagy, Csilla Kriston, Ildikó Krencz, Sándor Paku, Olivér Ozohanics, László Drahos, András Jeney and Anna Sebestyén

Journal of Experimental and Clinical Cancer Research


Rapid ascorbate response to bacterial elicitor treatment in Arabidopsis thaliana cells

Ádám Czobor, Péter Hajdinák, András Szarka

Acta Physiologiae Plantarum


D19S Mutation of the Cationic, Cysteine-Rich Protein PAF: Novel Insights into Its Structural Dynamics, Thermal Unfolding and Antifungal Function

Christoph Sonderegger, Ádám Fizil, Laura Burtscher, Dorottya Hajdú, Alberto Munoz, Zoltán Gáspári, Nick D. Read, Gyula Batta, Florentine Marx

PLOS One


A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway

Margita Márton, Anita Kurucz, Beáta Lizák, Éva Margittai, Gábor Bánhegyi, Orsolya Kapuy

International Journal of Molecular Science


GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy

Marianna Holczer, Gábor Bánhegyi, Orsolya Kapuy

PLOS One


Expression of mTORC1/2-related proteins in primary and brain metastatic lung adenocarcinoma

Ildikó Krencz, Anna Sebestyén, Katalin Fábián, Ágnes Márk, Judit Moldvay, András Khoor, László Kopper, Judit Pápay

Elsevier - Human Pathology


Structural determinants governing S100A4-induced isoform-selective disassembly of nonmuscle myosin II filaments

Bence Kiss, Lajos Kalmár, László Nyitray and Gábor Pál

The FEBS Journal



The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond

József Dobó, Gábor Pál, László Cervenak, Péter Gál

Immunological Reviews


mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression

Tamás Sticz, Anna Molnár, Ágnes Márk, Melinda Hajdu, Noémi Nagy, Gyula Végső, Tamás Micsik, László Kopper, Anna Sebestyén

Journal of Clinical Pathology


Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation

Noémi Nagy, Melinda Hajdu, Ágnes Márk, Péter Attila Király, Mónika Tóth, Titanilla Dankó, Mónika Csóka, Anna Sebestyén

International Society of Oncology and BioMarkers - Tumor Biology


Multiplex determination of antigen specific antibodies with cellbinding capability in a self-driven microfluidic system

Krisztián Papp, Eszter Holczer, Csilla Kecse-Nagy, Zoltán Szittner, Veronika Lóránd, Paolo Rovero, József Prechl, Péter Fürjes

Sensors and Actuators B: Chemical


The origin of the dual fluorescence of protonated ellipticine in water

Zsombor Miskolczy, László Biczók and István Jablonkai

Natural Sciences


Linking TP53 mutation to energy metabolism and glycolytic efficiency in breast cancer

Hajnalka Harami-Papp, Lőrinc S Pongor, Gergo Horvath, Adam M Nagy, Attila Ambrus, Péter Hauser, András Szabó, Laszlo Tretter and Balázs Győrffy

BBA - Bioenergetics


Composite Aromatic Boxes for Enzymatic

Gergely N. Nagy, Lívia Marton, Alicia Contet, Olivér Ozohanics, Laura-Mihaela Ardelean, Ágnes Révész, Károly Vékey, Florin Dan Irimie, Henri Vial, Rachel Cerdan and Beáta G. Vértessy

Enzyme Recognition


Phenilalanine ammonia-lyase catalyzed deamination

Diána Weiser, László Csaba Bencze, Gergely Bánóczi, Ferenc Ender , Róbert Kiss, Eszter Kókai , András Szilágyi, Beáta G Vértessy, Ödön Farkas and Csaba Paizs



Dynamics of re-constitution of the human nuclear proteome after cell division is regulated

Gergely Rona, Máté Borsos, Jonathan J Ellis, Ahmed M Mehdi, Mary Christie, Zsuzsanna Környei, Máté Neubrandt, Judit Tóth, Zoltán Bozóky, László Buday, Emília Madarász, Mikael Bodén, Bostjan Kobe and Beáta G Vértessy

NLS-adjacent phosphorylation


The Level of ALR

Tibor Balogh, Tamás Lőrincz, Ibolya Stiller, József Mandl, Gábor Bánhegyi and András Szarka

the Quantity of Mitochondrial DNA


Structural biology and regulation of protein import

Mary Christie, Chiung-Wen Chang, Gergely Róna, Kate M. Smith, Alastair G. Stewart, Agnes A.S. Takeda, Marcos R.M. Fontes, Murray Stewart, Beáta G. Vértessy, Jade K. Forwood and Bostjan Kob

Journal of Molecular Biology


Metastasis-associated S100A4 is a specific amine donor

Beáta Biri, Bence Kiss, Róbert Király, Gitta Schlosser, Orsolya Láng, László Kőhidai, László Fésüs and László Nyitray


Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights

Gergely Róna, Mary Marfori, Máté Borsos, Ildikó Scheer, Enikő Takács, Judit Tóth, Fruzsina Babos, Anna Magyar, Anna Erdei, Zoltán Bozóky, László Buday, Bostjan Kobe and Beáta G. Vértessy

Electronic Reprint


Detection of uracil within DNA using

Gergely Róna, Ildikó Scheer, Kinga Nagy, Hajnalka L. Pálinkás, Gergely Tihanyi, Máté Borsos, Angéla Békési and Beáta G. Vértessy

Nucleic Acids Research Advance Access


Differential detergent sensitivity

Xabier Osteikoetxea, Barbara Sódar, Andrea Németh, Katalin Szabó-Taylor, Krisztina Pálóczi, Krisztina V. Vukman, Viola Tamási, Andrea Balogh, Ágnes Kittel, Éva Pállingera and Edit Irén Buzás

Organic & Biomolecular Chemistry


Exploring the role of the phage-specific

Kinga Nyíri, Veronika Papp-Kádár, Judit E. Szabó, Veronika Németh and Beáta G. Vértessy

Springer Science+Business Media


Sensitive Phenotype of CHO-MT58 Cell Line

Lívia Marton, Gergely N. Nagy, Olivér Ozohanics, Anikó Lábas, Balázs Krámos, Julianna Oláh, Károly Vékey and Beáta G. Vértessy

MolecularMechanismfortheThermo


System and Substrate Docking Mechanism

Gergő Gógl, Kyle D. Schneider, Brian J. Yeh, Nashida Alam, Alex N.Nguyen Ba, Alan M. Moses,Csaba Hetényi, Attila Reményi and Eric L. Weiss


The mechanism of ageing

Ádám Sturm, Zoltán Ivics and Tibor Vellai

Cellular and Molecular Life Sciences


A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

Marianna Holczer, Margita Márton, Anita Kurucz, Gábor Bánhegyi and Orsolya Kapuy

Research Article


Cross-species inhibition of dUTPase

Rita Hirmondó, Judit E. Szabó, Kinga Nyíri, Szilvia Tarjányi, Paula Dobrotka, Judit Tóth and Beáta G. Vértessy

DNA Repair


Sensivity of Melanoma Cells

Tamás Garay, Eszter Molnár, Éva Juhász, Viktória László, Tamás Barbai, Judit Dobos, Karin Schelch, Christine Pirker, Michael Grusch, Walter Berger, József Tímár and Balázs Hegedűs

Oncogenic BRAF and NRAS Mutations


Composition of the redox environment of the endoplasmic reticulum and sources of hydrogenperoxide

Éva Margittai, Balázs Enyedi, Miklós Csala, Miklós Geiszt and Gábor Bánhegyi

Free Radical Biology and Medicine


On the role of 4-hydroxynonenal in health and disease

Miklós Csala, Tamás Kardon, Balázs Legeza, Beáta Lizák, József Mandl, Éva Mergittai, Ferenc Puskás, Péter Száraz, Péter Szelényi and Gábor Bánhegyi

Biochimica et Biophysica Acta


Prenylation Inhibition-Induced Cell Death is Melanoma

Tamás Garay, István Kenessey, Eszter Molnár, Éva Juhász, Andrea Réti, Viktória László, Anita Rózsás, Judit Dobos, Balázs Döme, Walter Berger, Walter Klepetko, József Tóvári, József Tímár and Balázs Hegedűs

PTENWild-TypeMelanomaCells


NLS copy-number variation governs efficiency

Gergely Róna, Hajnalka L. Palinkás, Máté Borsos, András Horváth, Ildikó Scheer, András Benedek, Gergely N. Nagy, Imre Zagyva and Beáta G. Vértessy

Case study on dUTPases


Highly potent dUTPase inhibition by a bacterial

Judit E. Szabó, Veronika Németh, Veronika Papp-Kádár, Kinga Nyíri, Ibolya Leveles, Ábris Á. Bendes, Imre Zagyva, Gergely Róa, Hajnalka L. Pálinkás, Balázs Besztercei, Olivér Ozohanics, Károly Vékey, Károly Liliom, Judit Tóth and Beáta G. Vértessy

Nucleic Acids Research Advance Access


Factors influencing nucleo-cytoplasmic trafficking

Gergely Róna, Máté Borsos, Bostjan Kobeb and Beáta G. Vértessy

Biological Crystallography


Preventive DNA repair by sanitizing the cellular

Gergely N. Nagy, Ibolya Leveles and Beáta G. Vértessy

The Febs Journal