May 28, 2020 06:00AM
To May 28, 2020 06:00PM
May 28. 2020 at 1:00 p.m
Tim Skern (Max Perutz Lab, Vienna): SARS-CoV2 structural biology – anti-viral and vaccine prospects
An integrated structural biology approach to investigate interactions between viral and host macromolecules
There is already an astonishing wealth of structure biological information available on coronavirus proteins, including some from SARS-CoV2. In the talk, I will discuss how this information will aid the development of vaccines and anti-viral agents and which information is still required. I will also discuss pitfalls and hurdles that may arise during vaccine and anti-viral development.
Ferenc Jakab (PTE): The importance of new and re-invasive infectious diseases today
The global threat and spread of communicable diseases poses a serious social and health risk to all nations. In addition to solving local problems, joint national and international cooperation is needed in all cases. In recent years, an increasing number of new infectious diseases have appeared or intensified in Hungary as well, which pose a significant threat. In my presentation, I will focus on the spread of emerging and re-emerging infectious diseases, their potential social and health effects, and the control possibilities.
Imre Kacskovics (ELTE): Development of a therapeutically targeted hACE2-Fc fusion protein
Péter Gál (TTK), Gábor Pál (ELTE): Proteases in our body: Friends or enemies?
There are ~700 protein-cleaving enzymes, proteases in our body, participating in all vital functions from fertilization, embryo- and ontogenesis through immune response and blood coagulation to the regulation of various endocrine systems. Misregulation of these proteases or protease cascades can lead to severe diseases. It is known that many pathogen microbes exploit the activity of host proteases to establish infection. The recently emerged SARS CoV-2 coronavirus causing the COVID-19 pandemic has such an infection mechanism. Selective inhibition of proteases that play roles in the infection process and the severe pathologic processes is therefore a promising therapeutic approach.
István Csabai (ELTE): Data-intensive approach in sciences
In the last two decades, almost every field of science - and perhaps it is no exaggeration to say that life - has been radically transformed by the technological explosion. High-capacity instruments have enabled measurements and observations in several disciplines, which have significantly refined our image of the world and created the basis for many new applications. In the presentation, I will try to illustrate the data-intensive research approach through examples and what kind of results, opportunities and challenges the accelerated computer technology and data avalanche have brought.