The Role of a Key Amino Acid Position in Species-Specific Proteinaceous dUTPase Inhibition

András Benedek, Fanni Temesváry-Kis, Tamjidmaa Khatanbaatar, Ibolya Leveles, Éva Viola Surányi, Judit Eszter Szabó, Lívius Wunderlich and Beáta G. Vértessy

2019-06-06 Biomolecules


HDX and Native Mass Spectrometry Reveals the Different Structural Basis for Interaction of the Staphylococcal Pathogenicity Island Repressor Stl with Dimeric and Trimeric Phage dUTPases

Kinga Nyíri, Matthew J. Harris, Judit Matejka, Olivér Ozohanics, Károly Vékey, Antoni J. Borysik and Beáta G. Vértessy

2019-09-14 Biomolecules


Beyond Chelation: EDTA Tightly Binds Taq DNA Polymerase, MutT and dUTPase and Directly Inhibits dNTPase Activity

Anna Lopata, Balázs Jójárt, Éva V. Surányi, Eniko ̋ Takács, László Bezúr, Ibolya Leveles, Ábris Á. Bendes, Béla Viskolcz, Beáta G. Vértessy and Judit Tóth

2019-10-17 Biomolecules


High-throughput competitive fluorescence polarization assay reveals functional redundancy in the S100 protein family

Márton A. Simon1 , Péter Ecsédi, Gábor M. Kovács, Adám L. Póti, Attila Reményi, József Kardos, Gergő Gógl and László Nyitray

2019-12-10 The FEBS Journal


The potential role of acrolein in plant ferroptosis-like cell death

Péter Hajdinák, Adám Czobor, András Szarka

2019-12-30 PLOS ONE


Investigation of Neutral Losses and the Citrulline Effect for Modified H4 N‐Terminal Pentapeptides

Arnold Steckel, Katalin Uray, Gergo Kalló, Éva Csosz, and Gitta Schlosser

2020-01-21 Journal of the American Society for Mass Spectrometry


Structure-based inhibitor design of mutant RAS proteins—a paradigm shift

Kinga Nyíri, Gergely Koppány, Beáta G. Vértessy

2020-07-26 Cancer and Metastasis Reviews


Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme

Richard Izrael, Lívia Marton, Gergely N. Nagy, Hajnalka L. Pálinkás, Nóra Kucsma & Beáta G. Vértessy

2020-11-12 Scientific Reports


Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments

Hajnalka L Pálinkás, Angéla Békési, Gergely Róna, Lőrinc Pongor, Gábor Papp, Gergely Tihanyi, Eszter Holub, Adám Póti, Carolina Gemma,
Simak Ali, Michael J Morten, Eli Rothenberg, Michele Pagano, Dávid Szűts, Balázs Győrffy, Beáta G Vértessy

2020-09-21 eLife


Substrate Tunnel Engineering Aided by X‐ray Crystallography and Functional Dynamics Swaps the Function of MIO Enzymes

Zsófia Bata, Zsófia Molnár, Erzsébet Madaras, Bence Molnár, Evelin Sánta-Bell, Andrea Varga, Ibolya Leveles, Renzhe Qian, Friedrich Hammerschmidt, Csaba Paizs, Beáta G. Vértessy, and László Poppe

2021-03-17 ACS Catalysis


Vitamin C and cell death

András Szarka, Orsolya Kapuy, Tamás Lőrincz, Gábor Bánhegyi

2021-03-18 Antioxidants & Redox Signaling


Genetic Polymorphism of GSTP-1 Affects Cyclophosphamide Treatment of Autoimmune Diseases

Péter Hajdinák, Melinda Szabó, Emese Kiss, Lili Veress, Lívius Wunderlich and András Szarka

2020-03-28 Molecules


Drug Conjugation Induced Modulation of Structural and Membrane Interaction Features of Cationic Cell-Permeable Peptides

Edit Pári 1, Kata Horváti, Szilvia Bo ̋sze, Beáta Biri-Kovács, Bálint Szeder, Ferenc Zsila and Éva Kiss

2020-03-22 International Journal of Molecular Sciences


Transposable elements promote aging in Caenorhabditis elegans

Ádám Sturm, Eva Saskoi, Bernadette Hotzi, Anna Tarnoci, Janos Barna, Ferenc Bodnár, Himani Sharma, Tibor Kovács, Csaba Kerepesi, Andras Perczel, Zoltán Ivics and Tibor Vellai

2020-08-25 Nature Communications


Structural Characterization of Daunomycin-Peptide Conjugates by Various Tandem Mass Spectrometric Techniques

Adina Borbély, Lilla Pethő, Ildikó Szabó, Mohammed Al-Majidi, Arnold Steckel, Tibor Nagy, Sándor Kéki, Gergő Kalló, Éva Csősz, Gábor Mező and Gitta Schlosser

2021-02-06 International Journal of Molecular Sciences


Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Anikó Gaál, Tamás M. Garay, Ildikó Horváth, Domokos Máthé, Dávid Szöllősi, Dániel S. Veres, Jeremiah Mbuotidem, Tibor Kovács, József Tóvári, Ralf Bergmann, Christina Streli, Gergely Szakács, Judith Mihály, Zoltán Varga and Norbert Szoboszlai

2020-05-20 Pharmaceutics


Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone

Péter Ecsédi, Gergő Gógl, Henrietta Hóf, Bence Kiss, Veronika Harmat, László Nyitray

2020-08-04 Structure


Proteomimetic surface fragments distinguish targets by function

Attila Tököli, Beáta Mag, Éva Bartus, Edit Wéber, Gerda Szakonyi, Márton A. Simon, Ágnes Czibula, Éva Monostori, László Nyitray and Tamás A. Martinek

2020-09-10 Chemical Science


Binding Profile Mapping of the S100 Protein Family Using a High-throughput Local Surface Mimetic Holdup Assay

Márton A. Simon, Éva Bartus, Beáta Mag, Eszter Boros, Lea Roszjár, Gerg Gógl, Gilles Travé, Tamás A. Martinek, and László Nyitray

2020-12-02 bioRxiv


Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum

Zoltán Attila Nagy, Dávid Szakács, Eszter Boros, Dávid Héja, Eszter Vígh, Noémi Sándor, Mihály Józsi, Gábor Oroszlán, József Dobó, Péter Gál, Gábor Pál

2019-12-20 PLOS Pathogens


Advances in Understanding TKS4 and TKS5: Molecular Scaffolds Regulating Cellular Processes from Podosome and Invadopodium Formation to Differentiation and Tissue Homeostasis

Gyöngyi Kudlik, Tamás Takács, László Radnai, Anita Kurilla, Bálint Szeder, Kitti Koprivanacz, Balázs L. Merő, László Buday, and Virag Vas

2020-10-30 International Journal of Molecular Sciences


Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster

Ábel Fóthi , Orsolya Biró , Zsuzsa Erdei , Ágota Apáti & Tamás I. Orbán

2020-10-23 RNA Biology


Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37

Mayra Quemé-Peña, Maria Ricci, Tünde Juhász, Kata Horváti, Szilvia Bősze, Beáta Biri-Kovács, Bálint Szeder, Ferenc Zsila, and Tamás Beke-Somfai

2020-12-03 ACS Pharmacology & Translational Science


Effect of pH on the conformation of bovine serume albumin - gold bioconjugates

Bence Fehér, Jeppe Lyngsø, Boróka Bartók, Judith Mihály, Zoltán Varga, Róbert Mészáros, Jan Skov Pedersen, Attila Bóta, Imre Varga

2020-04-17 Journal of Molecular Liquids


Evaluation and modulation of DNA lesion bypass in an SV40 large T antigen-based in vitro replication system

Zoltán Szeltner, Adám Póti, Gábor M. Harami, Mihály Kovács and Dávid Szüts

2021-01-26 FEBS Open Bio


Stability and recovery issues concerning chondroitin sulfate disaccharide analysis

Gábor Tóth, Domonkos Pál, Károly Vékey, László Drahos, Lilla Turiák

2021-01-27 Analytical and Bioanalytical Chemistry


Selective TiO2 Phosphopeptide Enrichment of Complex Samples in the Nanogram Range

Gábor Tóth, Fanni Bugyi, Simon Sugár, Goran Mitulovic, Károly Vékey, Lilla Turiák and László Drahos

2020-12-17 separations